Set in the 1980s in New York City, gay medical students Matt and Jeff connect while working in a retro-virology lab. When HIV erupts, the fallout upends their relationship as their response to the rising epidemic pushes them along different paths, raising questions about their values as scientists and doctors and their responsibilities as gay men. A sprawling drama spanning the decade, Love + Science explores the difficulties of love during a crisis, the realities of scientific progress, and how to maintain hope in the midst of an epic struggle.